Mycotoxin Analysis in Food Products fulfills the status of food safety compliance
Mycotoxins are toxic secondary metabolites of low-molecular-weight natural products produced by certain fungi, including Aspergillus, Penicillium, and Fusarium, that can contaminate foods, feeds, and agricultural products when conditions are ideal. These toxins have serious consequences for human and animal health, including carcinogenic, immunosuppressive, and neurotoxic effects. Mycotoxins are classified into several types based on their chemical structure or the fungi that produce them, such as aflatoxins: which is produced by Aspergillus flavus and A. parasiticus; highly carcinogenic; ochratoxins: which are produced by Aspergillus and Penicillium; fumonisins which are produced by Fusarium species, affect the nervous system; zearalenone which is produced by an oestrogenic toxin from Fusarium; and also produced deoxynivalenol (DON) which is known as vomitoxin causes gastrointestinal issues.
What is Mycotoxin Analysis?
Mycotoxin analysis involves detecting and quantifying toxic secondary metabolites (mycotoxins) produced by specific fungi, such as Aspergillus, Penicillium, and Fusarium species, in food, feed, and agricultural products. Common mycotoxins include aflatoxins, ochratoxins, fumonisins, zearalenone, and deoxynivalenol. Mycotoxin analysis can be performed using a variety of methods, including enzyme-linked immunosorbent assays (ELISA), which are known for their quick and specific screening; high-performance liquid chromatography (HPLC), which is highly sensitive and accurate; liquid chromatography-mass spectrometry (LC-MS/MS), which is well known for precise quantification and identification of multiple mycotoxins; and thin-layer chromatography (TLC), which is cost-effective but less sensitive.
Significance of Mycotoxin Analysis
- Health Protection: Mycotoxins can cause severe health issues such as liver damage, immune suppression, cancer, and neurological disorders in humans and animals.
- Food Safety Compliance: Ensures that food and feed meet regulatory limits set by authorities like the FDA, FSSAI, EFSA, and WHO.
- Economic Impact: Prevents financial losses by detecting contamination early in the supply chain, avoiding product recalls and trade barriers.
- Agricultural Monitoring: Helps farmers and producers identify vulnerable crops and implement mitigation strategies.
Why Groundnuts are More Susceptible to Mycotoxin Contamination?
- Fungal Affinity: Peanuts are cultivated mainly in tropical and subtropical regions, whereas A. flavus and A. parasiticus are the main mycotoxigenic fungi actively dominated in this condition which produce aflatoxins.
- High Oil Content: The fat-rich environment in groundnuts supports fungal growth and toxin production.
- Warm and Humid Conditions: Groundnuts are often grown and stored in regions with high temperatures and humidity, which are ideal conditions for fungal growth.
- Poor Post-Harvest Handling: Inadequate drying and improper storage can lead to increased fungal colonization.
- Soil and Environmental Factors: Fungi in the soil or airborne spores can infect groundnuts during growth or harvesting.
Risks in the Laboratory During Mycotoxin Testing
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Cross-Contamination: Mycotoxin samples can contaminate lab equipment and surfaces, leading to false results or exposure risks.
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Toxic Exposure: Direct handling of mycotoxins can pose health hazards to lab personnel if inhaled, ingested, or absorbed through the skin.
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Waste Management Issues: Improper disposal of mycotoxin-containing waste can harm the environment and expose others to toxins.
How Cultivator Phyto lab contribute to your products safety and compliances
Our cutting-edge testing center delivers swift and precise evaluations to uncover, recognize, and measure the existence of mycotoxins within food products. Cultivator Phyto Lab also presents an all-encompassing, risk-focused mycotoxin and biotoxin examination package that comprises thorough screenings alongside confirmatory assessments. We provide an extensive array of in-depth testing for various mycotoxins, including Aflatoxins B1, B2, G1, G2, M1, Fumonisins B1, B2, B3, T-2 / HT-2 toxin, Ochratoxin A (OTA), Ergot alkaloids, Patulin, Fusarenone X, Diacetoxyscirpenol, and more. Mycotoxins like aflatoxin B1 are extremely hazardous, posing fatal risks and potential carcinogenic effects. This sophisticated testing methodology empowers businesses to uphold food safety standards and safeguard consumers by eliminating mycotoxins from their offerings.
Authors
Dr. Sanjoy Gupta (Ph.D)
Senior Officer- Training and Capacity Building
Dr. Sanjoy Gupta is a seasoned researcher with 13 years of experience across plant biotechnology, health science, nutrition, phytoplankton, and botanical studies. He has conducted research at reputed institutions like CSIR IIP, BSI, NIOT, and Cultivator Natural Products. With over a dozen published articles in national/international journals and thoughtful blog contributions, Dr. Gupta’s multidisciplinary expertise advances knowledge in holistic wellness and scientific innovation.
Satya P. Ary
M.Sc. in Food Science & Technology
With over six years of experience, Satya is a seasoned analytical chemist at Cultivator Phyto Lab. His expertise spans chemical instrumentation, including UPLCMSMS, LCMSMS, GCMSMS, and HPLC. He specializes in pesticide residue, mycotoxin analysis, vitamins, and fatty acid profiles—essential for compliance with global standards (EU, USFDA, APEDA, EIC, FSSAI). Satya actively contributes to research and quality control, ensuring precision and adherence to ISO/IEC 17025:2017
Reference :
- https://pmc.ncbi.nlm.nih.gov/articles/PMC164220/
- https://www.fda.gov/food/natural-toxins-food/mycotoxins
- Bediako, Kwabena Asare; Ofori, Kwadwo; Offei, Samuel Kwame; Dzidzienyo, Daniel; Asibuo, James Yaw; Amoah, Richard Adu . (2018). Aflatoxin contamination of groundnut (Arachis hypogaea L.): Predisposing factors and management interventions. Food Control, S0956713518305656–. doi: 10.1016/j.foodcont.2018.11.020
- Dorner, J. W.. (2008). Management and prevention of mycotoxins in peanuts. Food Additives & Contaminants: Part A, 25(2), 203–208. doi:10.1080/02652030701658357
- Awuchi CG, Ondari EN, Nwozo S, Odongo GA, Eseoghene IJ, Twinomuhwezi H, Ogbonna CU, Upadhyay AK, Adeleye AO, Okpala COR. Mycotoxins’ Toxicological Mechanisms Involving Humans, Livestock and Their Associated Health Concerns: A Review. Toxins (Basel). 2022 Feb 24;14(3):167. doi: 10.3390/toxins14030167. PMID: 35324664; PMCID: PMC8949390.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9324440/